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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
17.88
Human Site:
T1430
Identified Species:
43.7
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
T1430
R
R
T
V
H
R
E
T
G
S
G
G
W
P
N
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
M1458
R
K
T
I
Y
K
D
M
K
T
G
A
W
P
N
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
M1414
R
K
T
I
Y
K
D
M
K
T
G
A
W
P
N
Dog
Lupus familis
XP_538245
4526
502835
T1412
R
R
T
I
H
R
E
T
G
S
G
G
W
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
T1431
R
R
T
I
H
R
E
T
G
S
G
G
W
P
N
Rat
Rattus norvegicus
P98158
4660
519258
Q1595
T
M
R
T
V
I
V
Q
E
K
I
Y
W
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
T1428
R
R
T
I
H
K
E
T
G
S
G
G
W
P
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
T1433
R
R
T
I
H
K
E
T
G
I
G
G
W
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
K1639
T
D
R
Q
I
I
V
K
T
K
I
Y
W
P
N
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
Q1416
S
I
I
V
N
I
T
Q
L
E
G
G
W
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
40
40
93.3
N.A.
93.3
13.3
N.A.
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
20
40
P-Site Similarity:
100
80
80
100
N.A.
100
13.3
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
0
20
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
50
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
50
0
80
60
0
0
0
% G
% His:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
60
10
30
0
0
0
10
20
0
0
0
0
% I
% Lys:
0
20
0
0
0
40
0
10
20
20
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
20
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
90
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
10
0
0
0
20
0
0
0
0
0
0
0
% Q
% Arg:
70
50
20
0
0
30
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% S
% Thr:
20
0
70
10
0
0
10
50
10
20
0
0
0
0
0
% T
% Val:
0
0
0
20
10
0
20
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% W
% Tyr:
0
0
0
0
20
0
0
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _